General
Preferred name
OXYMORPHONE
Synonyms
OXYMORPHONE HYDROCHLORIDE ()
Oximorfona ()
NSC-19045 ()
Dihydroxymorphinone ()
Oxymorphone cii ()
NIH 10323 ()
Oxycodone hydrochloride impurity, oxymorphone- ()
7,8-dihydro-14-hydroxymorphinone ()
IDS-NO-003 ()
14-hydroxydihydromorphinone ()
Oxymorphone hcl ()
Opana Er ()
Numorphan ()
Opana ()
Oxymorphone (hydrochloride) ()
P&D ID
PD009750
CAS
76-41-5
357-07-3
Tags
drug
available
Approved by
FDA
First approval
1959
Drug indication
Pain
Drug Status
vet_approved
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
TOXICITY Oxymorphone overdosage is characterized by respiratory depression, extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. Patients experiencing an overdose may develop apnea, circulatory collapse, and cardiac arrest. Intravenous mouse LD50 is 172 mg/kg.; ;
DESCRIPTION Oxymorphone is a semi-synthetic opioid drug. (GtoPdb)
Cell lines
0
Organisms
2
Compound Sets
12
Cayman Chemical Bioactives
15911
29435
ChEMBL Approved Drugs
CHEMBL963
CHEMBL1200794
ChEMBL Drugs
CHEMBL963
CHEMBL1200794
DrugBank
DB01192
DrugBank Approved Drugs
DB01192
DrugCentral
2034
DrugCentral Approved Drugs
2034
DrugMAP
DM65AGJ
DrugMAP Approved Drugs
DM65AGJ
Guide to Pharmacology
7094
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL963
NCATS Inxight Approved Drugs
9VXA968E0C
External IDs
50
Properties
(calculated by RDKit )
Molecular Weight
301.13
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
5
Aromatic Ring Count
1
cLogP
0.75
TPSA
70.0
Fraction CSP3
0.59
Chiral centers
4.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Neurology Agents
Source data