General
Preferred name
ACEBUTOLOL
Synonyms
ACEBUTOLOL HYDROCHLORIDE ()
Acebutolol HCl ()
Acebutolol (hydrochloride) ()
M&B 17803A ()
M&B-17803A ()
Acetanol ()
Sectral ()
Acebut HCl ()
Sectral 200 ()
Neptal ()
NSC-757412 ()
IL-17803A ()
B-17803A ()
Prent ()
Sectral 400 ()
B 17803A ()
C07AB04 ()
Acebutolol-d7 ()
P&D ID
PD009749
CAS
34381-68-5
37517-30-9
28197-63-9
2701782-36-5
Tags
natural product
drug
available
Approved by
FDA
First approval
1984
Drug Status
investigational
approved
Drug indication
Hypertension
Anti-Adrenergic (beta-receptor)
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Acebutolol is a β-blocker.
(GtoPdb)
DESCRIPTION
Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
27
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
Ki Database
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
63
Molecular Weight
336.2
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
10
Ring Count
1
Aromatic Ring Count
1
cLogP
2.37
TPSA
87.66
Fraction CSP3
0.56
Chiral centers
1.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuronal Signaling
Target
??-adrenergic receptor
ADRB1
Adrenergic Receptor
Indication
hypertension, ventricular arrhythmias
MOA
Adrenergic Receptor antagonist
Therapeutic Class
Antihypertensive Agents
Source data
