General
Preferred name
ZOPICLONE
Synonyms
ESZOPICLONE ()
Zileze 7.5 ()
Imovane ()
NSC-758463 ()
RP-27267 ()
Zileze 3.75 ()
RP 27267 ()
Amoban ()
Zimovane ()
Zimovane LS ()
Zopiclone-d4 ()
Zopiclone (CRM) ()
Zopiclone-d4 (CRM) ()
P&D ID
PD009745
CAS
43200-80-2
138680-07-6
1169825-88-0
1435933-78-0
Tags
natural product
drug
available
Approved by
FDA
First approval
2004
Drug Status
approved
Drug indication
Insomnia
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Zopiclone is a racemic mixture of the R and S chemical stereoisomers (PubChem CID 941731 and respectively). Eszopiclone is an approved drug in its own right.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
Axon Medchem Screening Library
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
Ki Database
LSP-MoA library (Laboratory of Systems Pharmacology)
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Molecular Weight
388.11
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
2
cLogP
1.57
TPSA
91.76
Fraction CSP3
0.35
Chiral centers
1.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
GABA(A) Receptor Modulators
Target
Benzodiazepine agonist
Therapeutic Class
Hypnotics and Sedatives
Source data
