General
Preferred name
CLIDINIUM
Synonyms
CLIDINIUM BROMIDE ()
Ro 2-3773 ()
Clidinium (bromide) ()
Quarzan ()
Ro-23773 ()
RO-2-3773 ()
NSC-756686 ()
Clidinium ion ()
Clidinium cation ()
Clidinium (bromide) ()
P&D ID
PD009727
CAS
3485-62-9
7020-55-5
Tags
available
drug
Approved by
FDA
Drug indication
Irritable bowel syndrome
Abdominal stomach pain
Anticholinergic
Drug Status
approved
Max Phase
Phase 4
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Clidinium is an antagonist of the muscarinic M1 and M3 acetylcholine receptors. The branded drug Librax® contains clidinium bromide and .
(GtoPdb)
DESCRIPTION
Clidinium bromide is an anticholinergic used as an antispasmodic to reduce stomach acid and decreases intestinal spasms.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
352.19
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
2
cLogP
2.7
TPSA
46.53
Fraction CSP3
0.41
Chiral centers
1.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
GPCR/G protein
Neuronal Signaling
Target
mAChR
AChR
Therapeutic Class
Analgesics
Solubility
Soluble in DMSO
Source data
