General
Preferred name
FOSFOMYCIN
Synonyms
phosphonomycin calcium salt ()
phosphomycin calcium ()
phosphonomycin calcium ()
Fosfomycin Tromethamine ()
Phosphomycin calcium salt ()
FOSFOMYCIN CALCIUM ()
Phosphomycin ()
Monuril ()
fosfomycin trometol ()
Fosfomycin Disodium ()
Fosfomycin (calcium) ()
FOSFOMYCIN SODIUM ()
MK-?0955 (calcium) ()
Phosphonemycin Disodium ()
J01XX01 ()
Fosfocina ()
Monurol ()
Fosfomycin Calcium ()
Zti-01 ()
Fosfomycin calcium hydrate ()
NSC-758170 ()
Calcium fosfomycin ()
Z-1282 ()
Fosfomycin trometamol (1:1) ()
Fosfomycin trometamol salt ()
Fosfomycin trometamol ()
Z 1282 ()
Phosphomycin disodium ()
NSC-136017 ()
Fosfomycin (calcium salt) ()
P&D ID
PD009701
CAS
78964-85-9
26016-98-8
26472-47-9
23155-02-4
26016-99-9
Tags
covalent binder
drug candidate
natural product
drug
available
Approved by
FDA
First approval
1996
Drug Status
investigational
approved
Drug indication
Bacterial infection
Antibacterial
Max Phase
Phase 4
Phase 3
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Fosfomycin is a phosphonic acid antibacterial, with broad antibacterial activity against Gram +ve and Gram -ve pathogens . It was originally isolated from certain types of Streptomyces, but it is now made synthetically. (GtoPdb)
Compound Sets
21
Cayman Chemical Bioactives
35535
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
CHEMBL1757
CHEMBL1200331
ChEMBL Drugs
CHEMBL1757
CHEMBL1200331
CHEMBL2322189
CovBinderInPDB
CBR002220
CBR003417
CBR005534
CBR005535
CBR005536
CBR005537
CBR007023
Drug Repurposing Hub
DrugBank
DB00828
DrugBank Approved Drugs
DB00828
DrugCentral
1243
DrugCentral Approved Drugs
1243
DrugMAP
DMVGPMX
DrugMAP Approved Drugs
DMVGPMX
Enamine BioReference Compounds
Guide to Pharmacology
10813
MedChem Express Bioactive Compound Library
HY-B1075
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
2N81MY12TE
NPC Screening Collection
Pandemic Response Box
Selleckchem Bioactive Compound Library
fosfomycin-disodium
TargetMol Bioactive Compound Library
T0170
T3131
T4989
External IDs
93
Properties
(calculated by RDKit )
Molecular Weight
138.01
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
-0.09
TPSA
70.06
Fraction CSP3
1.0
Chiral centers
2.0
Largest ring
3.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
bacterial enolpyruvate transferase inhibitor
bacterial cell wall synthesis inhibitor
Target
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
antibiotic
Bacterial
Antibiotics,Bacterial
Pathway
Microbiology/virology
Microbiology&virology
Anti-infection
Indication
urinary tract infections
Therapeutic Indication
Antibacterial
Therapeutic Class
Antimicrobial
Antibiotics
Source data