General
Preferred name
FOSFOMYCIN
Synonyms
phosphonomycin calcium salt ()
Fosfomycin Disodium ()
Phosphomycin ()
Monuril ()
fosfomycin trometol ()
Fosfomycin (sodium) ()
Fosfomycin (calcium) ()
MK-0955 (sodium) ()
MK-?0955 (calcium) ()
Phosphonemycin Disodium ()
FOSFOMYCIN CALCIUM ()
FOSFOMYCIN SODIUM ()
Fosfomycin Tromethamine ()
Fosfomycine ()
J01XX01 ()
Fosfomicina ()
Calcium fosfomycin ()
Zti-01 ()
Fosfomycin calcium hydrate ()
NSC-758170 ()
Fosfocina ()
Fosfomycin Calcium ()
Monurol ()
Fosfomycin trometamol (1:1) ()
Fosfomycin trometamol salt ()
Z 1282 ()
Z-1282 ()
Fosfomycin trometamol ()
Phosphomycin disodium ()
NSC-136017 ()
Fosfomycin (calcium salt) ()
Phosphonic acid, [(2R,?3S)?-?3-?methyloxiranyl]?-?, calcium salt ()
P&D ID
PD009701
CAS
26016-98-8
23155-02-4
78964-85-9
26016-99-9
26472-47-9
Tags
available
covalent binder
drug
drug candidate
Approved by
FDA
First approval
1996
Drug indication
infection
Pseudomonas infection
Bacterial infection
Drug Status
approved
investigational
Max Phase
3.0
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
31
DESCRIPTION
Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (phosphonomycin calcium) is an antibiotic, used for the treatment of urinary tract infections and intestinal infections caused by susceptible strains.
DESCRIPTION
Fosfomycin is a phosphonic acid antibacterial, with broad antibacterial activity against Gram +ve and Gram -ve pathogens . It was originally isolated from certain types of Streptomyces, but it is now made synthetically.
(GtoPdb)
PRICE
29
PRICE
29
DESCRIPTION
Fosfomycin is a broad spectrum antibiotic used to treat uncomplicated urinary tract infections.
(Enamine Bioactive Compounds)
DESCRIPTION
An antibiotic produced by Streptomyces fradiae.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
23
Cayman Chemical Bioactives
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine Bioactive Compounds
Enamine BioReference Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
NPC Screening Collection
Pandemic Response Box
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
99
Molecular Weight
138.01
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
-0.09
TPSA
70.06
Fraction CSP3
1.0
Chiral centers
2.0
Largest ring
3.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
bacterial enolpyruvate transferase inhibitor
bacterial cell wall synthesis inhibitor
Target
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Antibacterial
antibiotic
Bacterial
Antibiotics,Bacterial
Indication
urinary tract infections
Therapeutic Class
Antimicrobial
Antibiotics
Pathway
Microbiology/virology
Anti-infection
Source data
