General
Preferred name
pseudoephedrine
Synonyms
PSEUDOEPHEDRINE HYDROCHLORIDE ()
SCH-4855 ()
Afrinol ()
Otrivine Mu-Cron ()
Novafed ()
Pseudoephedrine hydrochloride component of aleve-d ()
Pseudoephedrine hydrochloride component of isoclor ()
Pseudoephedrine hydrochloride component of semprex-d ()
Pseudoephedrine hydrochloride component of triacin-c ()
Pseudoephedrine hydrochloride component of corphed ()
Pseudoephedrine hcl ()
Galpseud Plus ()
Pseudoephedrine hydrochloride component of mucinex d ()
Pseudoephedrine hydrochloride component of hycofenix ()
Pseudoephedrine hydrochloride component of allegra-d ()
Pseudoephedrine hydrochloride component of advil allergy sinus ()
Pseudoephedrine hydrochloride component of allerfed ()
Pseudoephedrine hydrochloride component of bromfed-dm ()
Pseudoephedrine hydrochloride component of histafed ()
Sudafed 24 Hour ()
Pseudoephedrine hydrochloride component of benylin ()
Pseudoephedrine hydrochloride component of actifed ()
Otrinol ()
Sudafed ()
Pseudophed ()
Pseudoephedrine hydrochloride component of dimetane-dx ()
Dimotane Plus L.A. ()
Pseudoephedrine hydrochloride component of zutripro ()
NSC-106567 ()
Dimotane Plus ()
Sinutab ()
Pseudoephedrine hydrochloride component of actahist ()
Rhinalair ()
Pseudoephedrine hydrochloride component of triphed ()
Pseudoephedrine hydrochloride component of rezira ()
Sudafed Plus ()
Efidac 24 ()
Sudafed 12 Hr Decongest ()
Galpseud ()
Pseudoephedrine hydrochloride component of zyrtec-d ()
Actifed ()
Pseudoephedrine hydrochloride component of children's advil cold ()
Pseudoephedrine hydrochloride component of codimal-l.a. 12 ()
Contac ()
Sudafed-SA ()
Galsud ()
Pseudoephedrine hydrochloride component of myfed ()
Pseudoephedrine hydrochloride component of children's motrin cold ()
Pseudoephedrine hydrochloride component of bromanate dm ()
NSC-33634 ()
Pseudoephedrine hydrochloride component of trilitron ()
Pseudoephedrine hydrochloride component of sine-aid ib ()
Sudafed 12 Hour ()
Neodurasina ()
Pseudoefedrina ()
Isoephedrine, d- ()
Acunaso ()
Pseudoephedrine sulfate component of drixoral plus ()
Pseudoephedrine sulfate component of claritin-d ()
Pseudoephedrine sulfate component of brompheril ()
Pseudoephedrine sulphate ()
Pseudoephedrine sulfate component of drixoral ()
D-pseudoephedrine sulfate ()
Pseudoephedrine sulfate component of disobrom ()
Pseudoephedrine sulfate component of trinalin ()
SCH 4855 ()
Pseudoephedrine sulfate component of resporal ()
Pseudoephedrine sulfate component of disophrol ()
Pseudoephedrine sulfate component of clarinex-d ()
PSEUDOEPHEDRINE SULFATE ()
(1S,2S)-(+)-Pseudoephedrine ()
Pseudoephedrine-d3 (hydrochloride) ()
(1S,2S)-(+)-Pseudoephedrine (hydrochloride) ()
P&D ID
PD009687
CAS
345-78-8
304-87-0
90-82-4
284665-25-4
Tags
available
drug
Approved by
FDA
First approval
1975
1963
Drug indication
Common cold
Allergic rhinitis
Nasal congestion
Seasonal allergic rhinitis
Drug Status
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pseudoephedrine is a decongestant, often contained as one of the active ingredients in fixed-mixture cold and flu medications. (GtoPdb)
Compound Sets
14
Cayman Chemical Bioactives
26508
14209
22494
ChEMBL Approved Drugs
CHEMBL1200724
CHEMBL1590
CHEMBL3989855
ChEMBL Drugs
CHEMBL1200724
CHEMBL1590
CHEMBL3989855
Drug Repurposing Hub
DrugBank
DB00852
DrugBank Approved Drugs
DB00852
DrugCentral
2326
DrugCentral Approved Drugs
2326
DrugMAP
DMIVJ0D
DrugMAP Approved Drugs
DMIVJ0D
Guide to Pharmacology
7286
NPC Screening Collection
Other bioactive compounds
The Spectrum Collection
External IDs
144
Properties
(calculated by RDKit )
Molecular Weight
165.12
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.33
TPSA
32.26
Fraction CSP3
0.4
Chiral centers
2.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Disease Area
cardiology, pulmonary, neurology/psychiatry, endocrinology
Indication
hypotension, asthma, narcolepsy, obesity
Target
ADRA1A, ADRA2A, ADRB1, ADRB2, ATF1, ATF2, ATF3, ATF4, ATF5, ATF6, ATF7, FOS, IL2, JDP2, JUN, NFATC1, SLC6A2, SLC6A3, SLC6A4, TNF
MOA
Adrenergic Receptor agonist
Source data