General
Preferred name
pseudoephedrine
Synonyms
PSEUDOEPHEDRINE HYDROCHLORIDE ()
SCH-4855 ()
Afrinol ()
PSEUDOEPHEDRINE SULFATE ()
(1S,2S)-(+)-Pseudoephedrine ()
Pseudoephedrine-d3 (hydrochloride) ()
Pseudoephedrine hydrochloride component of benylin ()
Pseudoephedrine hydrochloride component of semprex-d ()
Otrivine Mu-Cron ()
Pseudoephedrine hydrochloride component of advil allergy sinus ()
Pseudoephedrine hydrochloride component of mucinex d ()
Actifed ()
Pseudoephedrine hydrochloride component of bromanate dm ()
Pseudoephedrine hydrochloride component of children's motrin cold ()
Galpseud ()
Pseudoephedrine hydrochloride component of bromfed-dm ()
Sudafed ()
Dimotane Plus L.A. ()
Sudafed 12 Hr Decongest ()
Galsud ()
Pseudoephedrine hydrochloride component of corphed ()
Otrinol ()
Pseudoephedrine hcl ()
Pseudoephedrine hydrochloride component of myfed ()
Pseudoephedrine hydrochloride component of zutripro ()
Pseudoephedrine hydrochloride component of sine-aid ib ()
NSC-33634 ()
Efidac 24 ()
Pseudoephedrine hydrochloride component of trilitron ()
Pseudoephedrine hydrochloride component of triacin-c ()
Dimotane Plus ()
Pseudoephedrine hydrochloride component of actifed ()
Pseudoephedrine hydrochloride component of hycofenix ()
Pseudoephedrine hydrochloride component of allerfed ()
Pseudoephedrine hydrochloride component of actahist ()
Sudafed-SA ()
Contac ()
Pseudoephedrine hydrochloride component of allegra-d ()
Sinutab ()
Sudafed 12 Hour ()
Pseudoephedrine hydrochloride component of histafed ()
Pseudoephedrine hydrochloride component of rezira ()
Sudafed 24 Hour ()
Pseudoephedrine hydrochloride component of isoclor ()
Rhinalair ()
Pseudoephedrine hydrochloride component of triphed ()
Sudafed Plus ()
Pseudoephedrine hydrochloride component of codimal-l.a. 12 ()
Pseudoephedrine hydrochloride component of aleve-d ()
Pseudoephedrine hydrochloride component of dimetane-dx ()
Pseudophed ()
Novafed ()
NSC-106567 ()
Pseudoephedrine hydrochloride component of zyrtec-d ()
Pseudoephedrine hydrochloride component of children's advil cold ()
Galpseud Plus ()
Isoephedrine, d- ()
Acunaso ()
Neodurasina ()
Pseudoefedrina ()
Pseudoephedrine sulfate component of resporal ()
Pseudoephedrine sulfate component of brompheril ()
Pseudoephedrine sulfate component of disophrol ()
Pseudoephedrine sulfate component of drixoral plus ()
Pseudoephedrine sulfate component of disobrom ()
Pseudoephedrine sulphate ()
Pseudoephedrine sulfate component of clarinex-d ()
Pseudoephedrine sulfate component of drixoral ()
Pseudoephedrine sulfate component of trinalin ()
D-pseudoephedrine sulfate ()
Pseudoephedrine sulfate component of claritin-d ()
SCH 4855 ()
P&D ID
PD009687
CAS
345-78-8
304-87-0
90-82-4
284665-25-4
Tags
available
drug
Approved by
FDA
First approval
1963
1975
Drug indication
Nasal congestion
Common cold
Seasonal allergic rhinitis
Allergic rhinitis
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pseudoephedrine is a decongestant, often contained as one of the active ingredients in fixed-mixture cold and flu medications. (GtoPdb)
Compound Sets
14
Cayman Chemical Bioactives
14209
22494
ChEMBL Approved Drugs
CHEMBL1200724
CHEMBL1590
CHEMBL3989855
ChEMBL Drugs
CHEMBL1200724
CHEMBL1590
CHEMBL3989855
Drug Repurposing Hub
DrugBank
DB00852
DrugBank Approved Drugs
DB00852
DrugCentral
2326
DrugCentral Approved Drugs
2326
DrugMAP
DMIVJ0D
DrugMAP Approved Drugs
DMIVJ0D
Guide to Pharmacology
7286
NPC Screening Collection
Other bioactive compounds
The Spectrum Collection
External IDs
75
Properties
(calculated by RDKit )
Molecular Weight
165.12
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.33
TPSA
32.26
Fraction CSP3
0.4
Chiral centers
2.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Disease Area
cardiology, pulmonary, neurology/psychiatry, endocrinology
Indication
hypotension, asthma, narcolepsy, obesity
Target
ADRA1A, ADRA2A, ADRB1, ADRB2, ATF1, ATF2, ATF3, ATF4, ATF5, ATF6, ATF7, FOS, IL2, JDP2, JUN, NFATC1, SLC6A2, SLC6A3, SLC6A4, TNF
MOA
Adrenergic Receptor agonist
Source data