General
Preferred name
pseudoephedrine
Synonyms
PSEUDOEPHEDRINE HYDROCHLORIDE ()
SCH-4855 ()
Afrinol ()
PSEUDOEPHEDRINE SULFATE ()
Sudafed Plus ()
Actifed ()
Dimotane Plus L.A. ()
Pseudophed ()
Efidac 24 ()
Dimotane Plus ()
Novafed ()
Sudafed 24 Hour ()
Pseudoephedrine hcl ()
NSC-106567 ()
Rhinalair ()
Contac ()
Sudafed 12 Hr Decongest ()
Sudafed ()
Otrivine Mu-Cron ()
Otrinol ()
Galsud ()
NSC-33634 ()
Sudafed-SA ()
Galpseud ()
Galpseud Plus ()
Sinutab ()
Sudafed 12 Hour ()
Neodurasina ()
Pseudoephedrine polistirex ()
Acunaso ()
Isoephedrine, d- ()
SCH 4855 ()
Pseudoephedrine sulphate ()
D-pseudoephedrine sulfate ()
Pseudoephedrine-d3 (hydrochloride) ()
(1S,2S)-(+)-Pseudoephedrine ()
P&D ID
PD009687
CAS
345-78-8
304-87-0
90-82-4
284665-25-4
Tags
natural product
drug
available
Approved by
FDA
First approval
1975
1963
Drug Status
approved
Drug indication
Nasal congestion
Adrenergic (vasoconstrictor),Decongestant,Nasal Decongestant
Adrenergic (vasoconstrictor)
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Pseudoephedrine is a decongestant, often contained as one of the active ingredients in fixed-mixture cold and flu medications. (GtoPdb)
Compound Sets
14
Cayman Chemical Bioactives
14209
22494
ChEMBL Approved Drugs
CHEMBL1200724
CHEMBL1590
CHEMBL3989855
ChEMBL Drugs
CHEMBL1200724
CHEMBL1590
CHEMBL3989855
Drug Repurposing Hub
DrugBank
DB00852
DrugBank Approved Drugs
DB00852
DrugCentral
2326
DrugCentral Approved Drugs
2326
DrugMAP
DMIVJ0D
DrugMAP Approved Drugs
DMIVJ0D
Guide to Pharmacology
7286
NPC Screening Collection
Other bioactive compounds
The Spectrum Collection
External IDs
73
Properties
(calculated by RDKit )
Molecular Weight
165.12
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.33
TPSA
32.26
Fraction CSP3
0.4
Chiral centers
2.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Disease Area
cardiology, pulmonary, neurology/psychiatry, endocrinology
Indication
hypotension, asthma, narcolepsy, obesity
Target
ADRA1A, ADRA2A, ADRB1, ADRB2, ATF1, ATF2, ATF3, ATF4, ATF5, ATF6, ATF7, FOS, IL2, JDP2, JUN, NFATC1, SLC6A2, SLC6A3, SLC6A4, TNF
MOA
Adrenergic Receptor agonist
Source data