General
Preferred name
levorphanol
Synonyms
Dromoran ()
dextrorphan ()
LEVORPHANOL TARTRATE ()
IDS-NL-007 ()
Aromarone ()
RO 1-5431 ()
Levorphan ()
Levo-Dromoran ()
NSC-91012 ()
Levorphanol tartrate dihydrate ()
Levorphanol tartrate anhydrous ()
P&D ID
PD009686
CAS
125-74-6
297-90-5
77-07-6
Tags
drug
natural product
biased GPCR ligand
Approved by
FDA
First approval
1953
1991
Drug Status
approved
Drug indication
Analgesic (narcotic)
Ischemic stroke
Pain
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
BiasDB
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
NCATS Inxight Approved Drugs
NPC Screening Collection
Other bioactive compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Molecular Weight
257.18
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
4
Aromatic Ring Count
1
cLogP
3.08
TPSA
23.47
Fraction CSP3
0.65
Chiral centers
3.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Analgesics
Source data
