General
Preferred name
RANITIDINE
Synonyms
RANITIDINE HYDROCHLORIDE ()
HSDB 3925 ()
Ranitidine (hydrochloride) ()
AH19065 ()
AH-19065 ()
Ranitidine? (hydrochloride) ()
Ranitidine-d6 (hydrochloride) ()
P&D ID
PD009680
CAS
66357-59-3
66357-35-5
56131-49-8
71130-06-8
128345-62-0
82530-72-1
1185238-09-8
Tags
available
drug
Drug indication
Peptic ulcer
Drug Status
approved
withdrawn
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION There is some ambiguity in the exact stereochemistry of ranitidine as represented in the literature and on other databases. The structure shown here matches that in the PubChem entry above. Other common representations include CID 657345. N.B. The structure shown in the INN document does not have a charge.
Marketed formulations may contain ranitidine hydrochloride (PubChem CID 3033332). (GtoPdb)
DESCRIPTION H2 Histamine receptor antagonist; anti-ulcer agent (LOPAC library)
DESCRIPTION Ranitidine is an H2 histamine receptor antagonist that decreases the gastric secretion via blocking histamine. (BOC Sciences Bioactive Compounds)
Compound Sets
18
AdooQ Bioactive Compound Library
A17721
BOC Sciences Bioactive Compounds
ranitidine-cas-66357-35-5-item-13158
Cayman Chemical Bioactives
16939
22583
Concise Guide to Pharmacology 2017/18
1234
Concise Guide to Pharmacology 2019/20
1234
Concise Guide to Pharmacology 2021/22
1234
Concise Guide to Pharmacology 2023/24
1234
DrugMAP
DM0GUSX
DrugMAP Approved Drugs
DM0GUSX
Guide to Pharmacology
1234
LOPAC library
Mcule NIBR MoA Box Subset
MCULE-2682233624
MedChem Express Bioactive Compound Library
HY-B0281A
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Selleckchem Bioactive Compound Library
Ranitidine-hydrochloride(Zantac)
ranitidine
The Spectrum Collection
External IDs
43
Properties
(calculated by RDKit )
Molecular Weight
314.14
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
2
Rotatable Bonds
10
Ring Count
1
Aromatic Ring Count
1
cLogP
1.46
TPSA
83.58
Fraction CSP3
0.54
Chiral centers
0.0
Largest ring
5.0
QED
0.38
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
H2
Member status
member
MOA
Histamine H2 Receptor Antagonists
Therapeutic Class
Antiulcer Agents
Pathway
Anti-infection
GPCR/G protein
Immunology/Inflammation
Metabolic Enzyme/Protease
Neuronal Signaling
Target
Bacterial
Cytochrome P450
Histamine Receptor
Source data