General
Preferred name
PEMIROLAST
Synonyms
PEMIROLAST POTASSIUM ()
BMY 26517 ()
TWT-8152 ()
Pemirolast (potassium) ()
BMY26517 ()
Pemirolast (potassium salt) ()
Permirolast potassium ()
Pemirolast potassium salt ()
Alamast ()
BMY-26517 ()
Alegysal ()
Pemilaston ()
Pemirox ()
Permirolast ()
P&D ID
PD009663
CAS
69372-19-6
100299-08-9
Tags
available
drug
Approved by
FDA
First approval
1999
Drug indication
Abdominal aortic aneurysm
Allergic conjunctivitis
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
31
DESCRIPTION
Pemirolast is an antihistamine.
Marketed formulations may contain pemirolast potassium salt (PubChem CID 443866). (GtoPdb)
Marketed formulations may contain pemirolast potassium salt (PubChem CID 443866). (GtoPdb)
DESCRIPTION
Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx into mast cells.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
21
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
69
Molecular Weight
228.08
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
3
cLogP
0.18
TPSA
88.83
Fraction CSP3
0.1
Chiral centers
0.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Neuronal Signaling
MOA
Histamine Receptor antagonist
mediator release inhibitor
Indication
asthma
Target
HRH1
Histamine Receptor
H1 receptor
Therapeutic Class
Antiallergic Agents
Source data
