General
Preferred name
ethanol
Synonyms
ALCOHOL ()
ETHYL ALCOHOL ()
Ethanol ()
PM-6193-200 ()
Alcohol, Diluted ()
Alcohol 95% ()
Alcohol,sda ()
Ethanol, anhydrous ()
Vodka ()
FEMA NO. 2419 ()
Tecsol ()
NSC-85228 ()
Ethyl alcohol, absolute ()
Methylated Mineral ()
Anhydrous ethanol ()
Surg ()
Ethyl alcohol, dehydrated ()
Edible alcohol ()
Grain alcohol ()
Alcohol determination--alcohol ()
Alcohol denat. ()
Alcoholum ()
Alcohol, denatured ()
Alcohol, dehydrated ()
Alcohol,dehydrated ()
Ablysinol ()
Dehydrated alcohol ()
Alcohol, Rubbing ()
Ethanolum ()
Alcohol 190 proof ()
Dehydrated ethanol ()
Alcohol,ethyl ()
Ethylicum ()
Ethanol in alcoholic beverages ()
Ethanol, dehydrated ()
Alcohol, absolute ()
Sd alcohol ()
NCI-C03134 ()
Alcohol,denatured ()
E1510 ()
Spirigel ()
Alcohol denatured ()
B3324 ()
Alcohol anhydrous ()
Ethanol Residual Solvent (CRM) ()
P&D ID
PD009657
CAS
121182-78-3
64-17-5
68475-56-9
Tags
available
drug
Approved by
FDA
First approval
1946
Drug Status
approved
Drug indication
Cystitis
Anti-Infective, Topical
Chronic pain
Pharmaceutic Aid (solvent)
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
MOA
Ethanol affects the brainâs neurons in several ways. It alters their membranes as well as their ion channels, enzymes, and receptors. Alcohol also binds directly to the receptors for acetylcholine, serotonin, GABA, and the NMDA receptors for glutamate. ; The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). It also inhibits NMDA receptor functioning. In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes.
DESCRIPTION
The US FDA granted approval for the use of an injectable formulation of ethanol (alcohol) in dextrose solution, but marketing has been discontinued.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2023/24
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
NCATS Inxight Approved Drugs
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
46.04
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
0.0
TPSA
20.23
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
Molecular Weight
46.04
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
0.0
TPSA
20.23
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Analgesics
Source data
