General
Preferred name
ethanol
Synonyms
ALCOHOL ()
ETHYL ALCOHOL ()
Edible alcohol ()
Alcohol component of hbn-1 ethanol ()
Ablysinol ()
Surg ()
Alcohol,dehydrated ()
Anhydrous ethanol ()
Alcohol denatured ()
E1510 ()
Alcohol anhydrous ()
Dehydrated ethanol ()
Ethylicum ()
FEMA NO. 2419 ()
Ethyl alcohol, absolute ()
Vodka ()
Alcohol,denatured ()
Dehydrated alcohol ()
Methylated Mineral ()
Ethyl alcohol, dehydrated ()
Alcohol determination--alcohol ()
Ethanol ()
Alcohol, dehydrated ()
PM-6193-200 ()
Spirigel ()
Alcohol 95% ()
Alcohol, absolute ()
NCI-C03134 ()
Ethanolum ()
Alcohol,sda ()
Ethanol, anhydrous ()
Alcohol, denatured ()
B3324 ()
Tecsol ()
Ethanol, dehydrated ()
Sd alcohol ()
Alcohol denat. ()
Alcohol,ethyl ()
Alcohol component of avagard ()
Alcohol 190 proof ()
Alcoholum ()
NSC-85228 ()
Grain alcohol ()
Ethanol in alcoholic beverages ()
P&D ID
PD009657
CAS
121182-78-3
64-17-5
68475-56-9
Tags
available
drug
Approved by
FDA
First approval
1946
1982
Drug indication
infection
Cystitis
Chronic pain
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
MOA Ethanol affects the brain’s neurons in several ways. It alters their membranes as well as their ion channels, enzymes, and receptors. Alcohol also binds directly to the receptors for acetylcholine, serotonin, GABA, and the NMDA receptors for glutamate. ; The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). It also inhibits NMDA receptor functioning. In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes.
DESCRIPTION The US FDA granted approval for the use of an injectable formulation of ethanol (alcohol) in dextrose solution, but marketing has been discontinued. (GtoPdb)
Compound Sets
13
ChEMBL Approved Drugs
CHEMBL545
ChEMBL Drugs
CHEMBL545
Concise Guide to Pharmacology 2023/24
2299
DrugBank
DB00898
DrugBank Approved Drugs
DB00898
DrugCentral
1076
DrugCentral Approved Drugs
1076
DrugMAP
DMDRQZU
DrugMAP Approved Drugs
DMDRQZU
DrugMatrix
Guide to Pharmacology
2299
NCATS Inxight Approved Drugs
3K9958V90M
ReFrame library
External IDs
45
Properties
(calculated by RDKit )
Molecular Weight
46.04
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
0.0
TPSA
20.23
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
Molecular Weight
46.04
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
0.0
TPSA
20.23
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.41
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Therapeutic Class
Analgesics
Source data