General
Preferred name
SPECTINOMYCIN
Synonyms
SPECTINOMYCIN HYDROCHLORIDE ()
Spectinomycin HCl ()
Spectinomycin hydrochloride hydrate ()
Trobicin ()
Spectogard ()
Spectinomycin 2HCl ()
Actinospectacin ()
Spectinomycin dihydrochloride ()
Spectinomycin (dihydrochloride) ()
Spectinomycin (dihydrochloride pentahydrate) ()
Spectinomycin (hydrochloride hydrate) ()
Trobicin, Spectinomycin hydrochloride hydrate ()
Spectinomycin dihydrochloride pentahydrate ()
NSC-757319 ()
Spectinomycini hydrochloridum ()
NSC-248616 ()
U-18,409AE ()
Spectinomycin hydrochloride pentahydrate ()
Spectinomycin hcl pentahydrate ()
U-18409AE ()
M-141 ()
Espectinomicina ()
Adspec ()
CHX-3101 ()
Spectinomycine ()
Prospec ()
P&D ID
PD009642
CAS
22189-32-8
21736-83-4
1695-77-8
Tags
available
drug
natural product
Approved by
FDA
First approval
1971
Drug indication
osteomyelitis
Bacterial infection
Drug Status
vet_approved
approved
withdrawn
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
PRICE 29
DESCRIPTION Spectinomycin is an aminocyclitol aminoglycoside bacteriostatic antibacterial. It was isolated from Streptomyces spectabilis. Spectinomycin is active against gram-negative bacteria. (GtoPdb)
DESCRIPTION Spectinomycin is an aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. (Enamine Bioactive Compounds)
DESCRIPTION Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea. (TargetMol Bioactive Compound Library)
DESCRIPTION Spectinomycin dihydrochloride pentahydrate (Spectogard) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
24
AdooQ Bioactive Compound Library
A10861
Cayman Chemical Bioactives
14324
ChEMBL Approved Drugs
CHEMBL3989571
CHEMBL1167
ChEMBL Drugs
CHEMBL3989571
CHEMBL1167
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB00919
DrugBank Approved Drugs
DB00919
DrugCentral
2468
DrugCentral Approved Drugs
2468
DrugMAP
DM0MQ35
DrugMAP Approved Drugs
DM0MQ35
Enamine Bioactive Compounds
EBC-11140
Enamine BioReference Compounds
Guide to Pharmacology
11127
MedChem Express Bioactive Compound Library
HY-B0438
HY-B1828A
NIH Clinical Collections (NCC)
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
Spectinomycin-hydrochloride
spectinomycin-dihydrochloride-pentahydrate
TargetMol Bioactive Compound Library
T0788
T0788L
The Spectrum Collection
Withdrawn 2.0
1001
External IDs
93
Properties
(calculated by RDKit )
Molecular Weight
332.16
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
5
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
0
cLogP
-2.93
TPSA
129.51
Fraction CSP3
0.93
Chiral centers
9.0
Largest ring
6.0
QED
0.36
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
30S ribosome
antibiotic
Bacterial
Antibiotics,Antibiotics for Mammalian Cell Culture,Selection Antibiotics for Transfected Cell
Antibiotics,Bacterial
Indication
airsacculitis, chronic respiratory disease
MOA
bacterial 30S ribosomal subunit inhibitor
ATC
J01XX04
Pathway
Microbiology/virology
Anti-infection
Therapeutic Class
Antibiotics
Source data