General
Preferred name
CYCRIMINE
Synonyms
CYCRIMINE HYDROCHLORIDE ()
Cicrimina ()
Cycrimine HCl ()
Pagitane ()
NSC-169452 ()
P&D ID
PD009627
CAS
77-39-4
107661-05-2
Tags
available
drug
Approved by
FDA
Drug indication
Parkinson disease
Drug Status
withdrawn
approved
Max Phase
4.0
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
ReFrame library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Properties
(calculated by RDKit )
Molecular Weight
287.22
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
1
cLogP
3.94
TPSA
23.47
Fraction CSP3
0.68
Chiral centers
1.0
Largest ring
6.0
QED
0.89
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
N
Pathway
GPCR/G protein
Neuronal Signaling
Therapeutic Class
Antiparkinson Agents
Target
mAChR
Source data
