General
Preferred name
BROMFENAC
Synonyms
Bromfenac (sodium hydrate) ()
Bromfenac monosodium salt sesquihydrate ()
Bromfenac sodium hydrate ()
BROMFENAC SODIUM ()
Bromfenac (sodium) ()
Lomb-1 ()
bromfenac (low concentration), Bausch & ()
AHR 10282R,Bromsite,Bromday,Prolensa,Xibrom ()
Bromsite, Bromday, Prolensa, Xibrom ()
Bromfenac monosodium salt ()
Bromfenac sodium sesquihydrate ()
Bromsite ()
AHR-10282B ()
Bromday ()
Xibrom ()
Prolensa ()
Bromfenac sodium anhydrous ()
ISV-303 ()
Yellox ()
Bromfenac (sodium salt) ()
Bromfenac-d4 (sodium salt) ()
P&D ID
PD009615
CAS
120638-55-3
91714-94-2
91714-93-1
2749400-35-7
Tags
available
drug
Approved by
FDA
First approval
1997
2005
Drug Status
approved
withdrawn
Drug indication
Inflammation
Postoperative inflammation
Analgesic
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID).
Marketed formulations may contain bromfenac sodium (PubChem CID 23693301). (GtoPdb)
Compound Sets
26
AdooQ Bioactive Compound Library
A13244
Cayman Chemical Bioactives
23763
26598
ChEMBL Approved Drugs
CHEMBL751
CHEMBL1077
ChEMBL Drugs
CHEMBL751
CHEMBL1077
Concise Guide to Pharmacology 2019/20
7131
Concise Guide to Pharmacology 2021/22
7131
Concise Guide to Pharmacology 2023/24
7131
Drug Repurposing Hub
DrugBank
DB00963
DrugBank Approved Drugs
DB00963
DrugCentral
401
DrugCentral Approved Drugs
401
DrugMAP
DMKB79O
DrugMAP Approved Drugs
DMKB79O
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
EOS102306
Guide to Pharmacology
7131
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1077
MedChem Express Bioactive Compound Library
HY-B1888A
NCATS Inxight Approved Drugs
864P0921DW
NPC Screening Collection
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
bromfenac-sodium-hydrate
bromfenac-sodium
TargetMol Bioactive Compound Library
T2403
Withdrawn 2.0
w174
External IDs
71
Properties
(calculated by RDKit )
Molecular Weight
333.0
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
2.89
TPSA
80.39
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
1
anthranil_one_A(38)
c:1:c:c:c:c(:c:1-[#7&!H0;!H1,!$([#7]-[#6]=[#8])])-[#6](-[#6]:[#6])=[#8]
PAINS Family B
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Neuroscience
Target
COX-2
PTGS1, PTGS2
COX
MOA
COX inhibitor
cyclooxygenase inhibitor
ATC
S01BC11
Toxicity type
hepatic
Therapeutic Class
Antiinflammatory Agents
Source data