General
Preferred name
levobupivacaine
Synonyms
(S)-(-)-Bupivacaine monohydrochloride ()
LEVOBUPIVACAINE HYDROCHLORIDE ()
(S)-(-)-Bupivacaine HCl ()
Levobupivacaine HCl ()
Levobupivacaine hydrochloride(S)-(-)-Bupivacaine HCl ()
Levobupivacaine (hydrochloride) ()
Chirocaine, (S)-(-)-Bupivacaine, L-(-)-Bupivacaine ()
Bupivacaine (-)-form hydrochloride ()
Chirocaine ()
Levobupivac ()
(-)-bupivacaine ()
(s)-bupivacaine ()
Bupivacaine, (-)- ()
L-bupivacaine ()
Bupivacaine, (s)- ()
Bupivacaine (-)-form ()
Novabupi ()
Levobupivacaine-d9 (hydrochloride) ()
P&D ID
PD009597
CAS
27262-48-2
27262-47-1
Tags
natural product
drug
available
Approved by
FDA
First approval
1999
Drug Status
investigational
approved
Drug indication
Anaesthesia
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
This drug is the (S)-enantiomer of .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
56
Properties
(calculated by RDKit )
Molecular Weight
288.22
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
1
cLogP
3.9
TPSA
32.34
Fraction CSP3
0.61
Chiral centers
1.0
Largest ring
6.0
QED
0.89
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Apoptosis
Target
Sodium Channel
KCNA5, SCN10A
Ferroptosis
Indication
peripheral nerve block, caudal epidural block, lumbar epidural block
MOA
Sodium Channel blocker
Therapeutic Class
Anesthetics
Source data