General
Preferred name
Balsalazide
Synonyms
BALSALAZID ()
Balsalazide disodium dihydrate ()
Balsalazide sodium hydrate ()
BALSALAZIDE DISODIUM ()
Balsalazide disodium salt dihydrate ()
Balsalazide Sodium ()
Balsalazide (sodium hydrate) ()
Colazal, Giazo ()
Balsalazide sodium ()
Colazide ()
Giazo ()
Colazal ()
Balsalazide disodium anhydrous ()
BX661A ()
Balsalazine ()
NSC-760046 ()
BX-661A ()
Balsalazide-d4 ()
P&D ID
PD009593
CAS
150399-21-6
80573-04-2
82101-18-6
Tags
prodrug
natural product
drug
available
Approved by
FDA
First approval
2000
Drug Status
investigational
approved
Max Phase
Phase 4
Drug indication
Anti-Inflammatory (gastrointestinal)
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
Enamine BioReference Compounds
NCATS Inxight Approved Drugs
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
56
Properties
(calculated by RDKit )
Molecular Weight
357.1
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
2.71
TPSA
148.65
Fraction CSP3
0.12
Chiral centers
0.0
Largest ring
6.0
QED
0.56
Structural alerts
1
azo_A(324)
[#7;!R]=[#7]
PAINS Family A
Related compounds
Custom attributes
(extracted from source data)
Pathway
JAK/STAT Signaling
Immunology/Inflammation
Stem Cell/Wnt
Target
STAT
ALOX5, PPARG, PTGS1, PTGS2
Interleukin Related
Immunology & Inflammation related,Interleukins,STAT
Indication
ulcerative colitis
MOA
cyclooxygenase inhibitor
Source data
