General
Preferred name
BETHANECHOL
Synonyms
BETHANECHOL CHLORIDE ()
Carbamyl-¦Â-methylcholine chloride ()
Carbamyl-¦Â-methylcholine ()
(±)-Bethanechol ()
Urecholine ()
Myocholine ()
Carbamyl-β-methylcholine chloride ()
(¡À)-Bethanechol ()
Carbamyl-??methylcholine chloride ()
Carbamyl-??methylcholine ()
Myocholine(¡À)-Bethanechol ()
Bethanechol (chloride) ()
Myocholine,Urecholine ()
Myotonachol ()
Duvoid ()
NSC-30783 ()
Myotonine ()
Bethanechol-d6 (chloride) ()
P&D ID
PD009590
CAS
590-63-6
674-38-4
21293-39-0
Tags
available
drug
Approved by
FDA
First approval
1948
Drug indication
eosinophilic esophagitis
Urinary retention
Drug Status
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Bethanechol chloride (Carbamyl-¦Â-methylcholine chloride), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].
PRICE 29
DESCRIPTION Bethanechol chloride (Carbamyl-??-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. It is used to increase smooth muscle tone in the GI tract following abdominal surgery or to treat urinary retention without obstruction. Possible side effects include hypotension, heart rate changes, and bronchial spasm.
DESCRIPTION Bethanechol is structurally and pharmacologically related to .
Marketed formulations may contain bethanechol chloride (PubChem CID 11548). (GtoPdb)
DESCRIPTION Muscarinic acetylcholine receptor agonist; resistant to acetylcholinesterase and non-specific cholinesterases (LOPAC library)
DESCRIPTION A selective muscarinic receptor stimulant, used to treat cerebral palsy. (BOC Sciences Bioactive Compounds)
DESCRIPTION Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. It is used to increase smooth muscle tone in the GI tract following abdominal surgery or to treat urinary retention without obstruction. Possible side effects include hypotension, heart rate changes, and bronchial spasm. (TargetMol Bioactive Compound Library)
Compound Sets
29
AdooQ Bioactive Compound Library
A10180
BOC Sciences Bioactive Compounds
bethanechol-chloride-cas-590-63-6-345824
Cayman Chemical Bioactives
23830
33299
ChEMBL Approved Drugs
CHEMBL1768
CHEMBL1482
ChEMBL Drugs
CHEMBL1768
CHEMBL1482
Concise Guide to Pharmacology 2017/18
297
Concise Guide to Pharmacology 2019/20
297
Concise Guide to Pharmacology 2021/22
297
Concise Guide to Pharmacology 2023/24
297
DrugBank
DB01019
DrugBank Approved Drugs
DB01019
DrugCentral
358
DrugCentral Approved Drugs
358
DrugMAP
DMCLHO0
DrugMAP Approved Drugs
DMCLHO0
DrugMatrix
Guide to Pharmacology
297
Ki Database
Bethanechol
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1482
MedChem Express Bioactive Compound Library
HY-B0406A
NCATS Inxight Approved Drugs
004F72P8F4
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Carbamyl-beta-methylcholine-chloride(Bethanechol-chloride)
TargetMol Bioactive Compound Library
T3126
The Spectrum Collection
External IDs
56
Properties
(calculated by RDKit )
Molecular Weight
161.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
0.18
TPSA
52.32
Fraction CSP3
0.86
Chiral centers
1.0
Largest ring
0.0
QED
0.6
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Muscarinic
Target
mAChR
muscarinic receptor
AChR
Pathway
Neuronal Signaling
GPCR/G protein
Neuroscience
Therapeutic Class
Parasympathomimetics
Solubility
Soluble in Water, Ethanol
Source data