General
Preferred name
PROCAINAMIDE
Synonyms
PROCAINAMIDE HYDROCHLORIDE ()
Procainamide HCl ()
Pronestyl ()
Procanbid ()
Procapan ()
Procainamide (hydrochloride) ()
Procaine amide ()
SP 100 ()
Procainamidi hydrochloridum ()
Pronestyl-SR ()
Biocoryl ()
Procan sr ()
Novocainamid ()
Cardiorytmin ()
Procan ()
NSC-757279 ()
Amidoprocaine ()
NSC-27461 ()
Novocainamide ()
Sp 100 (pharmaceutical) ()
P&D ID
PD009585
CAS
614-39-1
51-06-9
Tags
natural product
drug
available
Approved by
FDA
First approval
1950
Drug Status
approved
Drug indication
Ventricular arrhythmias
Cardiac Depressant (anti-arrhythmic)
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Procainamide is a class Ia antiarrhythmic drug. (GtoPdb)
DESCRIPTION Na+ channel blocker and Class I anti-arrhythmic (LOPAC library)
Compound Sets
29
Cayman Chemical Bioactives
24359
ChEMBL Approved Drugs
CHEMBL605
CHEMBL640
ChEMBL Drugs
CHEMBL605
CHEMBL640
Concise Guide to Pharmacology 2017/18
4811
Concise Guide to Pharmacology 2019/20
4811
Concise Guide to Pharmacology 2021/22
4811
Concise Guide to Pharmacology 2023/24
4811
Drug Repurposing Hub
DrugBank
DB01035
DrugBank Approved Drugs
DB01035
DrugCentral
2270
DrugCentral Approved Drugs
2270
DrugMAP
DMNMXR8
DrugMAP Approved Drugs
DMNMXR8
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
4811
Ki Database
Procainamide
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL640
MedChem Express Bioactive Compound Library
HY-A0084
HY-A0084A
NCATS Inxight Approved Drugs
L39WTC366D
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
procainamide-hcl
TargetMol Bioactive Compound Library
T0018
The Spectrum Collection
External IDs
58
Properties
(calculated by RDKit )
Molecular Weight
235.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
1
Aromatic Ring Count
1
cLogP
1.34
TPSA
58.36
Fraction CSP3
0.46
Chiral centers
0.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Chromatin/Epigenetic
Membrane Transporter/Ion Channel
Neuroscience
Autophagy
Epigenetics
Target
AChR
DNA (cytosine-5)-methyltransferase 1
Sodium Channel
DNMT1, SCN5A
DNA Methyltransferase
DNA Methyltransferase,Sodium Channel
Indication
ventricular arrhythmias, ventricular tachycardia (VT)
MOA
Sodium Channel blocker
Therapeutic Class
Antiarrhythmic Agents
Source data