General
Preferred name
RIFAMPICIN
Synonyms
RIFAMPIN ()
Rifamycin AMP ()
Rifampin (NSC-113926) ()
Rimactane, Rifampicin,NSC-113926 ()
NSC-113926 ()
L-5103 ()
Rifamycin amp ()
Rifampicin ()
Rifadin ()
Rifampicinum ()
Rifadine ()
Rifapiam ()
NIH-10782 ()
Rifaldazine ()
Rifaprodin ()
Rifaldin ()
Rifoldin ()
Abrifam ()
L-5103 LEPETIT ()
Rimactane ()
Rimactan ()
BA 411661E ()
Eremfat ()
L-5103-LEPETIT ()
BA-41166E ()
Rifampin ()
P&D ID
PD009580
CAS
13292-46-1
Tags
natural product
drug
available
Drug Status
approved
Drug indication
Antibacterial
Tuberculosis
Max Phase
Phase 4
First approval
1971
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION As with many natural products with complex structures, there is some ambiguity as to the exact structure of rifampicin. Common representations of the structure include CID 5458213, and CID 5381226. (GtoPdb)
Cell lines
3
Organisms
17
Compound Sets
22
Cayman Chemical Bioactives
14423
ChEMBL Approved Drugs
CHEMBL374478
ChEMBL Drugs
CHEMBL374478
Concise Guide to Pharmacology 2017/18
2765
Concise Guide to Pharmacology 2019/20
2765
Concise Guide to Pharmacology 2021/22
2765
Concise Guide to Pharmacology 2023/24
2765
Drug Repurposing Hub
DrugBank
DB01045
DrugBank Approved Drugs
DB01045
DrugMAP
DMA8J1G
DrugMAP Approved Drugs
DMA8J1G
EU-OPENSCREEN Bioactive Compound Library
EOS101641
EUbOPEN Chemogenomics Library
Guide to Pharmacology
2765
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL374478
MedChem Express Bioactive Compound Library
HY-B0272
NCATS Inxight Approved Drugs
VJT6J7R4TR
Novartis Chemogenetic Library (NIBR MoA Box)
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Rifampin(Rifadin)
External IDs
44
Properties
(calculated by RDKit )
Molecular Weight
822.41
Hydrogen Bond Acceptors
15
Hydrogen Bond Donors
6
Rotatable Bonds
4
Ring Count
6
Aromatic Ring Count
2
cLogP
4.34
TPSA
220.15
Fraction CSP3
0.53
Chiral centers
9.0
Largest ring
24.0
QED
0.11
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
DNA-Directed RNA Polymerase Inhibitors
Enzyme Inducers
RNA Polymerase (Bacterial) Inhibitors
RNA polymerase inhibitor
Indication
tuberculosis, meningitis
Target
NR1I2, SLCO1A2, SLCO1B1, SLCO1B3
antibiotic
Bacterial
Influenza Virus
Orthopoxvirus
Antibiotics for Plant Cell Culture,Antineoplastic and Immunosuppressive Antibiotics,DNA/RNA Synthesis,Selection Antibiotics for Transfected Cell
Therapeutic Class
Antituberculosis Agents
Pathway
Anti-infection
Source data