General
Preferred name
AZLOCILLIN
Synonyms
Sodium azlocillin ()
AZLOCILLIN SODIUM ()
Azlocillin sodium salt ()
Azlocillin ()
Azlocillin (sodium salt) ()
Azlin ()
Securopen ()
BAY-E-6905 ()
BAY-E 6905 ()
J01CA09 ()
Azlocilline ()
NSC-758227 ()
Azlocilina ()
P&D ID
PD009573
CAS
37091-66-0
37091-65-9
Tags
available
covalent binder
drug
Approved by
FDA
First approval
1982
Drug indication
bacterial disease
Pseudomonas infection
Drug Status
approved
withdrawn
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum ¦Â-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum[1][2][3].
PRICE
29
PHARMACODYNAMICS
Similar to [mezlocillin] and [piperacillin], azlocillin is an acylampicillin that exhibits an extended-spectrum of activity and _in vitro_ potency that is greater than that of the carboxy penicillins. Azlocillin is shown to be effective against a broad spectrum of bacteria, including Pseudomonas aeruginosa and enterococci.
DESCRIPTION
Azlocillin is a semisynthetic penicillin derivative belonging to the β-lactam class of antibacterial compounds.
(GtoPdb)
DESCRIPTION
Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Other bioactive compounds
Prestwick Chemical Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
51
Molecular Weight
461.14
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
1
cLogP
0.09
TPSA
148.15
Fraction CSP3
0.45
Chiral centers
4.0
Largest ring
6.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
Parasite
PBPs
Indication
gram-positive bacterial infections, gram-negative bacterial infections
MOA
bacterial cell wall synthesis inhibitor
ATC
J01CA09
Pathway
Microbiology/virology
Anti-infection
Therapeutic Class
Antibiotics
Source data
