General
Preferred name
ACETOPHENAZINE
Synonyms
ACETOPHENAZINE MALEATE ()
Tindal ()
Acetophenazine ()
Acetophenazine (dimaleate) ()
Acetophenazine dimaleate ()
SCH-6673 ()
NSC-169180 ()
SCH 6673 ()
NSC-70600 ()
Acephenazine Dimaleate ()
Acetophenazine (maleate) ()
P&D ID
PD009571
CAS
5714-00-1
2751-68-0
Tags
available
drug
Approved by
FDA
First approval
1961
Drug Status
approved
withdrawn
Drug indication
Bipolar disorder
Antipsychotic
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Ki Database
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
411.2
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
2
cLogP
3.49
TPSA
47.02
Fraction CSP3
0.43
Chiral centers
0.0
Largest ring
6.0
QED
0.7
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
DRD1, DRD2
Dopamine Receptor
Indication
psychosis
MOA
Dopamine Receptor antagonist
ATC
N05AB07
Therapeutic Class
Antipsychotic Agents
Pathway
GPCR/G protein
Neuronal Signaling
Source data
