General
Preferred name
Rolitetracycline
Synonyms
ROLITETRACYCLINE NITRATE ()
Synterin ()
SQ 15,659 ()
Syntetrin ()
NSC-759177 ()
SQ-15659 ()
SO 15,659 ()
Bristacin ()
Pyrrocycline-n ()
P&D ID
PD009567
CAS
751-97-3
Tags
prodrug
drug candidate
natural product
drug
available
Drug Status
approved
withdrawn
Drug indication
Antibacterial
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Rolitetracycline is a parenterally delivered prodrug of , an antibacterial that has activity against Gram-negative and Gram-positive bacteria.
Note that the structure shown here matches the CAS-assigned structure and is the same as the ChEBI and ChEMBL entries linked to below. There is no exact match in PubChem for the structure shown here. (GtoPdb)
Cell lines
0
Organisms
1
Compound Sets
9
Cayman Chemical Bioactives
23479
ChEMBL Drugs
CHEMBL1237046
CHEMBL2105868
DrugBank
DB01301
DrugBank Approved Drugs
DB01301
DrugCentral
2399
DrugCentral Approved Drugs
2399
Guide to Pharmacology
12760
MedChem Express Bioactive Compound Library
HY-18257
NPC Screening Collection
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
527.23
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
6
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
1
cLogP
0.47
TPSA
170.87
Fraction CSP3
0.52
Chiral centers
5.0
Largest ring
6.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Anti-infection
Target
antibiotic
Bacterial
Source data