General
Preferred name
FOSPHENYTOIN
Synonyms
ACC-9653 ()
FOSPHENYTOIN SODIUM ()
Fosphenytoin (disodium) ()
Np-06 ()
Fosphenytoine ()
Fosfenitoina ()
ACC-9653-010 (SODIUM SALT) ()
ACC-9653-010 ()
Sesquient ()
Fosphenytoin disodium salt ()
Cerebyx ()
Pro-Epanutin ()
CI 982 ()
CI-982 ()
Fosphenytoin (sodium salt) ()
P&D ID
PD009565
CAS
92134-98-0
93390-81-9
Tags
available
drug
prodrug
Approved by
FDA
First approval
1996
Drug indication
Anticonvulsant
Epilepsy
Drug Status
approved
investigational
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Fosphenytoin is a prodrug of phenytoin. This drug is an anticonvulsant.
Marketed formulations may contain fosphenytoin sodium (PubChem CID 56338). (GtoPdb)
Compound Sets
17
Cayman Chemical Bioactives
23889
ChEMBL Approved Drugs
CHEMBL1201336
CHEMBL919
ChEMBL Drugs
CHEMBL1201336
CHEMBL919
Drug Repurposing Hub
DrugBank
DB01320
DrugBank Approved Drugs
DB01320
DrugCentral
1247
DrugCentral Approved Drugs
1247
DrugMAP
DMOX3LB
DrugMAP Approved Drugs
DMOX3LB
DrugMatrix
Guide to Pharmacology
7190
MedChem Express Bioactive Compound Library
HY-B1657A
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
fosphenytoin
TargetMol Bioactive Compound Library
T7066
External IDs
58
Properties
(calculated by RDKit )
Molecular Weight
362.07
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
2
cLogP
1.55
TPSA
116.17
Fraction CSP3
0.12
Chiral centers
0.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Target
Sodium Channel
SCN5A
Indication
epilepsy, seizures
MOA
Sodium Channel blocker
Therapeutic Class
Anticonvulsants
Source data