General
Preferred name
POLYTHIAZIDE
Synonyms
Polythiazide ()
P-2525 ()
NSC-108161 ()
Nephril ()
Renese ()
P&D ID
PD009563
CAS
346-18-9
Tags
available
drug
Approved by
FDA
First approval
1961
Drug Status
approved
withdrawn
Drug indication
Diuretic
Hypertension
Antihypertensive
Edema
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Polythiazide is a thiazide diuretic.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
NPC Screening Collection
ReFrame library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
438.97
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
1
cLogP
1.66
TPSA
109.57
Fraction CSP3
0.45
Chiral centers
1.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
C03AA05
Therapeutic Class
Antihypertensive Agents
Source data
