General
Preferred name
PIPECURONIUM
Synonyms
Pipecuronium ()
Pipecuronium (bromide) ()
PIPECURONIUM BROMIDE ()
Pipecuronium bromide dihydrate ()
RGH-1106 ()
Pipecuronium bromide anhydrous ()
RGH 1106 ()
Arduan ()
Pipecurium bromide ()
Pipecuronium bromide hydrate ()
P&D ID
PD009548
CAS
68399-58-6
52212-02-9
Tags
available
drug
Approved by
FDA
First approval
1990
Drug Status
approved
withdrawn
Drug indication
Spasm
Neuromuscular Blocking Agent
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION A nondepolarizing neuromuscular blocking agent that inhibits neuromuscular transmission by competing with acetylcholine for the cholinergic receptors of the motor end plate, thereby reducing the response of the end plate to acetylcholine. It has been used as a muscle relaxant during anesthesia and surgical procedures. (BOC Sciences Bioactive Compounds)
Compound Sets
13
BOC Sciences Bioactive Compounds
pipecuronium-cas-68399-58-6-292595
ChEMBL Approved Drugs
CHEMBL1201206
CHEMBL1200722
ChEMBL Drugs
CHEMBL1201206
CHEMBL1200722
Drug Repurposing Hub
DrugBank
DB01338
DrugBank Approved Drugs
DB01338
DrugCentral
2183
DrugCentral Approved Drugs
2183
DrugMAP
DM5F84A
DrugMAP Approved Drugs
DM5F84A
MedChem Express Bioactive Compound Library
HY-B0743A
NPC Screening Collection
Withdrawn 2.0
1248
External IDs
43
Properties
(calculated by RDKit )
Molecular Weight
602.48
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
6
Aromatic Ring Count
0
cLogP
3.63
TPSA
59.08
Fraction CSP3
0.94
Chiral centers
10.0
Largest ring
6.0
QED
0.36
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
anesthetic
Target
CHRM2, CHRM3, CHRNA2
nAChR
MOA
neuromuscular blocker
ATC
M03AC06
Therapeutic Class
Analgesics
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data