General
Preferred name
FORASARTAN
Synonyms
SC-52458 ()
P&D ID
PD009545
CAS
145216-43-9
Tags
available
drug
Drug indication
Hypertension
Antihypertensive
Drug Status
experimental
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Forasartan is a nonpeptide, competitive and reversible angiotensin II receptor antagonist, selective for the AT1 receptor. Forasartan is not a popular drug of choice for hypertension as it is less effective than , due to its relatively short duration of action. (GtoPdb)
DESCRIPTION Forasartan, a tetrazol derivative, has been found to be a angiotensin II receptor antagonist that could be effective against hypertension through influencing the vasoconstriction and the formation of aldosterone. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
8
BOC Sciences Bioactive Compounds
forasartan-cas-145216-43-9-item-475794
ChEMBL Drugs
CHEMBL315021
DrugBank
DB01342
DrugMAP
DMRBJNZ
DrugMAP Approved Drugs
DMRBJNZ
DrugMatrix
Guide to Pharmacology
6896
ReFrame library
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
416.24
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
10
Ring Count
4
Aromatic Ring Count
4
cLogP
4.25
TPSA
98.06
Fraction CSP3
0.39
Chiral centers
0.0
Largest ring
6.0
QED
0.41
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Therapeutic Class
Antihypertensive Agents
Source data