General
Preferred name
TASOSARTAN
Synonyms
WAY-ANA 756 ()
ANA-756 ()
WAY-ANA-756 ()
P&D ID
PD009541
CAS
145733-36-4
Tags
available
drug
Drug indication
Hypertension
Antihypertensive
Drug Status
experimental
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tasosartan, a pyrido-pyrimidin derivative, has been found to be an angiotensin II receptor antagonist that could have probable effect against hypertension. It has been discontinued for some security problems by Wyeth. (BOC Sciences Bioactive Compounds)
Compound Sets
13
AdooQ Bioactive Compound Library
A10891
BOC Sciences Bioactive Compounds
tasosartan-cas-145733-36-4-item-58986
Cayman Chemical Bioactives
29495
ChEMBL Drugs
CHEMBL432162
DrugBank
DB01349
DrugCentral
3839
DrugCentral Approved Drugs
3839
DrugMAP
DMM13DI
DrugMAP Approved Drugs
DMM13DI
DrugMatrix
Guide to Pharmacology
6898
MedChem Express Bioactive Compound Library
HY-A0250
ReFrame library
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
411.18
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
4
cLogP
3.42
TPSA
100.55
Fraction CSP3
0.22
Chiral centers
0.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Therapeutic Class
Antihypertensive Agents
Pathway
GPCR/G protein
Target
Angiotensin Receptor
Source data