General
Preferred name
TROLEANDOMYCIN
Synonyms
Troleandomycin ()
troleandomycin, Elan ()
Triacetyloleandomycin ()
Acetyloleandomycin ()
NSC-108166 ()
Oleandomycin (as troleandomycin) ()
Oleandomycin triacetate ester ()
P&D ID
PD009533
CAS
2751-09-9
Tags
natural product
drug
available
Approved by
FDA
First approval
1969
Drug Status
approved
withdrawn
Drug indication
Bacterial infection
Antibacterial
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
ReFrame library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
27
Properties
(calculated by RDKit )
Molecular Weight
813.45
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
0
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
0
cLogP
3.62
TPSA
184.19
Fraction CSP3
0.88
Chiral centers
18.0
Largest ring
14.0
QED
0.19
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Disease Area
infectious disease, pulmonary, otolaryngology
Indication
pneumonia, bronchitis, tonsillitis, sinusitis
MOA
protein synthesis inhibitor
ATC
J01FA08
Pathway
Anti-infection
Metabolic Enzyme/Protease
Therapeutic Class
Antibiotics
Target
Bacterial
Cytochrome P450
Source data
