General
Preferred name
MEPHENTERMINE
Synonyms
MEPHENTERMINE SULFATE ()
Mephentermine hemisulfate ()
Mephentermine sodium ()
Wyamine Sulfate ()
Mephentermine sulfate dihydrate ()
NSC-758424 ()
Wyamine sulphate ()
Mephine ()
Wyamine ()
Mephentermine sulphate ()
P&D ID
PD009530
CAS
1212-72-2
100-92-5
Tags
natural product
drug
available
Approved by
FDA
First approval
1951
Drug Status
approved
withdrawn
Drug indication
High blood pressure
Adrenergic (vasoconstrictor)
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Mephentermine is a cardiac stimulant, but it does not belong to the cardiac glycosides drug family.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
Ki Database
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
52
Molecular Weight
163.14
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
2.23
TPSA
12.03
Fraction CSP3
0.45
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3
Indication
hypotension
MOA
Adrenergic Receptor agonist
ATC
C01CA11
Therapeutic Class
Vasoconstrictor Agents
Source data
