General
Preferred name
CEFPODOXIME
Synonyms
Cefpodoxime acid ()
R 3763 ()
Orelox Paed ()
Epoxim ()
Orelox ()
Cefpodoxime ()
Cefpodoxime ()
Cefpodoxime-d3 ()
P&D ID
PD009505
CAS
80210-62-4
2477791-28-7
Tags
available
drug
Drug Status
approved
vet_approved
Drug indication
Bacterial infection
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Cefpodoxime (proxetil) is a broad-spectrum, oral, third generation cephalosporin antibacterial that is active against most Gram-positive and Gram-negative bacteria .
(GtoPdb)
INDICATION
Indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms.
PHARMACODYNAMICS
Cefpodoxime is shown to be effective against most Gram positive and Gram negative bacteria, except Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis.
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
427.06
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
3
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
1
cLogP
-0.54
TPSA
156.44
Fraction CSP3
0.4
Chiral centers
2.0
Largest ring
6.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Antibiotics
Pathway
Anti-infection
Target
antibiotic
Bacterial
Source data
