General
Preferred name
ACENOCOUMAROL
Synonyms
Acenocoumarin ()
Nicoumalone ()
NSC-760052 ()
Sinthrome ()
Mini-sintrom ()
Acenocoumarol-d4 ()
P&D ID
PD009504
CAS
152-72-7
Tags
available
drug
Drug Status
investigational
approved
Drug indication
Thrombosis
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Acenocoumarol is a coumarin that is used as an anticoagulant, with actions and uses similar to . The coumarins are vitamin K epoxide reductase antagonists.
(GtoPdb)
INDICATION
For the treatment and prevention of thromboembolic diseases. More specifically, it is indicated for the prevention of cerebral embolism, deep vein thrombosis, pulmonary embolism, thromboembolism in infarction and transient ischemic attacks. It is used for the treatment of deep vein thrombosis and myocardial infarction.
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
ReFrame library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
353.09
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
3
cLogP
3.52
TPSA
110.65
Fraction CSP3
0.16
Chiral centers
1.0
Largest ring
6.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Target
vitamin K
Therapeutic Class
Anticoagulants
Source data
