General
Preferred name
APRINDINE
Synonyms
Aprindine hydrochloride ()
Compound 99170 ()
NSC-284614 ()
Aprindine hcl ()
Fibocil ()
Aprinidine chloride ()
Aspenon ()
COMPOUND 83846 ()
P&D ID
PD009497
CAS
37640-71-4
33237-74-0
Tags
available
drug candidate
drug
First approval
1996
Drug indication
Cardiac arrhythmias
Cardiac Depressant (anti-arrhythmic)
Drug Status
experimental
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
NPC Screening Collection
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
322.24
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
2
cLogP
4.39
TPSA
6.48
Fraction CSP3
0.45
Chiral centers
0.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
cardiac arrythmia
Target
CALM1, SCN5A
MOA
voltage-gated sodium channel blocker
Therapeutic Class
Antiarrhythmic Agents
Source data
