General
Preferred name
FLUNITRAZEPAM
Synonyms
[3H]flunitrazepam ()
Rohypnol ()
N05CD03 ()
RO-5-4200 ()
Ro-54200 ()
RO 5-4200 ()
Flunitrazepam-d7 (CRM) ()
Flunitrazepam-d3 ()
Flunitrazepam-d3 (exempt preparation) ()
P&D ID
PD009482
CAS
1622-62-4
1286448-08-5
219533-64-9
Tags
available
drug
First approval
1976
Drug Status
illicit
approved
withdrawn
Drug indication
Sedative-Hypnotic
Insomnia
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION A benzodiazepine with pharmacologic actions similar to those of diazepam. Due to illicit use of this drug importation has been banned by the US, but medicinal use is approved in other countries. (GtoPdb)
Compound Sets
20
Cayman Chemical Bioactives
16189
22855
19251
16188
ChEMBL Approved Drugs
CHEMBL13280
ChEMBL Drugs
CHEMBL13280
Concise Guide to Pharmacology 2017/18
4193
4360
Concise Guide to Pharmacology 2019/20
4193
4360
Concise Guide to Pharmacology 2021/22
4193
4360
Concise Guide to Pharmacology 2023/24
4193
4360
DrugBank
DB01544
DrugBank Approved Drugs
DB01544
DrugCentral
1202
DrugCentral Approved Drugs
1202
DrugMAP
DMGR5Z3
DrugMAP Approved Drugs
DMGR5Z3
DrugMatrix
Guide to Pharmacology
4193
4360
Ki Database
Flunitrazepam
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Withdrawn 2.0
w230
ZINC Tool Compounds
ZINC000003812994
External IDs
43
Properties
(calculated by RDKit )
Molecular Weight
313.09
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
2.55
TPSA
75.81
Fraction CSP3
0.12
Chiral centers
0.0
Largest ring
7.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
GABA(A) BZ Site Receptor Agonists
ATC
N05CD03
Toxicity type
multiple
Therapeutic Class
Hypnotics and Sedatives
Source data