General
Preferred name
CLOTIAZEPAM
Synonyms
Rize ()
Clozan ()
P&D ID
PD009476
CAS
33671-46-4
Tags
drug
available
Drug indication
Anxiety disorder
Anxiety
Drug Status
approved
investigational
illicit
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PHARMACODYNAMICS Clotiazepam is a benzodiazepine derivative possessing anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It increases the stage 2 non-rapid eye movement sleep.
Compound Sets
9
Cayman Chemical Bioactives
27745
ChEMBL Drugs
CHEMBL1697737
DrugBank
DB01559
DrugBank Approved Drugs
DB01559
DrugCentral
718
DrugCentral Approved Drugs
718
DrugMAP
DM59AZT
DrugMAP Approved Drugs
DM59AZT
DrugMatrix
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
318.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
3.78
TPSA
32.67
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
7.0
QED
0.83
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Therapeutic Class
Hypnotics and Sedatives
Source data