General
Preferred name
PRAZEPAM
Synonyms
Prazepam ()
W 4020 ()
NSC-277179 ()
Demetrin ()
W-4020 ()
Prazepam civ ()
Centrax ()
Prazepam (CRM) ()
P&D ID
PD009466
CAS
2955-38-6
Tags
available
drug
Approved by
FDA
Drug Status
illicit
approved
withdrawn
Drug indication
Anxiety disorder
Sedative-Hypnotic
Max Phase
Phase 4
First approval
1982
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PHARMACODYNAMICS Prazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. Benzodiazepines may be habit-forming (causing mental or physical dependence), especially when taken for a long time or in high doses.
DESCRIPTION Prazepam is a benzodiazepine type drug. (GtoPdb)
Compound Sets
14
Cayman Chemical Bioactives
21701
18358
ChEMBL Approved Drugs
CHEMBL969
ChEMBL Drugs
CHEMBL969
DrugBank
DB01588
DrugBank Approved Drugs
DB01588
DrugCentral
2240
DrugCentral Approved Drugs
2240
DrugMAP
DMEWC7N
DrugMAP Approved Drugs
DMEWC7N
DrugMatrix
Guide to Pharmacology
7275
NPC Screening Collection
ReFrame library
Withdrawn 2.0
415
External IDs
24
Properties
(calculated by RDKit )
Molecular Weight
324.1
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
2
cLogP
3.93
TPSA
32.67
Fraction CSP3
0.26
Chiral centers
0.0
Largest ring
7.0
QED
0.84
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
ATC
N05BA11
Therapeutic Class
Antianxiety Agents
Source data