General
Preferred name
MOLINDONE
Synonyms
MOLINDONE HYDROCHLORIDE ()
Minolteparin sodium molindone ()
EN-1733A ()
Molindone (hydrochloride) ()
Moban ()
Molindone hcl ()
Spn-810 ()
P&D ID
PD009446
CAS
15622-65-8
7416-34-4
65973-37-7
Tags
natural product
drug
available
Approved by
FDA
First approval
1974
Drug Status
approved
withdrawn
Drug indication
Antipsychotic
Schizophrenia
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Marketed formulations may contain molindone hydrochloride (PubChem CID 9883259).
(GtoPdb)
DESCRIPTION
D2 dopamine receptor antagonist; monoamine oxidase inhibitor
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
26
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
Ki Database
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
55
Molecular Weight
276.18
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
1
cLogP
1.96
TPSA
45.33
Fraction CSP3
0.69
Chiral centers
1.0
Largest ring
6.0
QED
0.92
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
D2
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
5-HT
mAChR
dopamine
D2 antagonist
Dopamine Receptor
ATC
N05AE02
Therapeutic Class
Antipsychotic Agents
Source data
