General
Preferred name
PHENIRAMINE
Synonyms
PHENIRAMINE MALEATE ()
Pheniramine bimaleate ()
Daneral ()
Inhiston ()
Trimetose ()
Trimeton ()
NSC-757270 ()
PM-241 ()
Daneral-Sa ()
Antolozine ()
Pheniramine maleate component of visine ()
Prophenpyridamine maleate ()
Pheniramine maleate component of naphcon-a ()
Pheniramine hydrogen maleate ()
Avil ()
Naphcon a ()
Pheniramine maleate component of visine-a ()
Fervex ()
Avil Ret ()
Tripoton ()
NSC-47965 ()
Feniramina ()
Pyriton ()
Propheniramine ()
Prophenpyridamine ()
Pheniramine (maleate) ()
P&D ID
PD009444
CAS
132-20-7
86-21-5
Tags
available
drug
Approved by
FDA
First approval
1994
Drug indication
Common cold
Hay fever
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Pheniramine is an antihistamine.
Marketed formulations may contain pheniramine maleate (PubChem CID 5282139). Pheniramine is often contained in fixed-ratio formulations alongside other antihistamines and agents such as decongestants. (GtoPdb)
Marketed formulations may contain pheniramine maleate (PubChem CID 5282139). Pheniramine is often contained in fixed-ratio formulations alongside other antihistamines and agents such as decongestants. (GtoPdb)
DESCRIPTION
H1 histamine receptor antagonist.
(LOPAC library)
DESCRIPTION
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived relaxing factor, nitric oxide.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
21
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Guide to Pharmacology
Ki Database
LOPAC library
NCATS Inxight Approved Drugs
NPC Screening Collection
Other bioactive compounds
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
59
Molecular Weight
240.16
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
3.17
TPSA
16.13
Fraction CSP3
0.31
Chiral centers
1.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
H1
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Therapeutic Class
Antiallergic Agents
Target
Histamine Receptor
HT
Source data
