General
Preferred name
TERLIPRESSIN
Synonyms
Terlipressin diacetate anhydrous ()
Terlipressin acetate anhydrous ()
Terlipressin Acetate ()
Terlipressin (diacetate) ()
Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys4-Cys9) ()
Terlipressin acetate ()
Glypressin ()
Glycylpressin ()
Variquel ()
Terlivaz ()
Terlipressin (acetate) ()
P&D ID
PD009427
CAS
1884420-36-3
14636-12-5
914453-96-6
Tags
available
drug
Approved by
FDA
First approval
2022
Drug indication
Hypertension
Drug Status
approved
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Terlipressin is a clinically used vasopressin analogue. Terlipressin is biotransformed to its active moiety, lysine vasopressin (LVP). It has vasoconstrictive, antihemorrhagic, and antidiuretic properties. (GtoPdb)
Compound Sets
14
Cayman Chemical Bioactives
27027
ChEMBL Approved Drugs
CHEMBL2135460
ChEMBL Drugs
CHEMBL2135460
Drug Repurposing Hub
DrugCentral
2967
DrugCentral Approved Drugs
2967
DrugMAP
DMT9FH3
DrugMAP Approved Drugs
DMT9FH3
Guide to Pharmacology
11241
MedChem Express Bioactive Compound Library
HY-12554A
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
terlipressin-acetate
TargetMol Bioactive Compound Library
T13920L
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
1226.5
Hydrogen Bond Acceptors
19
Hydrogen Bond Donors
16
Rotatable Bonds
25
Ring Count
4
Aromatic Ring Count
2
cLogP
-6.98
TPSA
512.85
Fraction CSP3
0.5
Chiral centers
8.0
Largest ring
20.0
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
vasopressin V1
AVPR1A
Vasopressin Receptor
5-alpha Reductase
Indication
hypotension
MOA
Vasopressin Receptor agonist
Therapeutic Class
Vasoconstrictor Agents
Source data