General
Preferred name
FUSIDIC ACID
Synonyms
Fusidine ()
Fusidic acid sodium salt ()
FUSIDATE ()
SQ-16603 ()
Fucidin Caviject ()
Taksta ()
SQ 16,603 ()
Fucithalmic ()
NSC-56192 ()
CEM-102 ()
Ramycin ()
Anhydrous fusidic acid ()
Acido fusidico ()
Acide fusidique ()
Fusidic Acid-d6 ()
P&D ID
PD009387
CAS
6990-06-3
Tags
available
drug
Drug indication
MRSA infection
Keloid
Bacterial infection
Drug Status
approved
investigational
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PHARMACODYNAMICS Fusidic acid is a bacteriostatic antibiotic and helps prevent bacterial growth while the immune system clears the infection.
DESCRIPTION Fusidic acid is an orally bioavailable fusidane antibacterial with activity against Gram +ve pathogens . (GtoPdb)
DESCRIPTION Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome. Fusidic acid holds promise for research in anticancer and anti-infective applications.[1][2][3][4][5].
PRICE 29
DESCRIPTION Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
2
Compound Sets
17
Cayman Chemical Bioactives
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
Pandemic Response Box
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
External IDs
45
Properties
(calculated by RDKit )
Molecular Weight
516.35
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
0
cLogP
5.67
TPSA
104.06
Fraction CSP3
0.81
Chiral centers
10.0
Largest ring
6.0
QED
0.25
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
CAT
elongation factor G (EF-G)
Indication
acne vulgaris (AV)
MOA
bacterial 30S ribosomal subunit inhibitor
Pathway
Microbiology/virology
Anti-infection
Therapeutic Class
Antibiotics
Source data