General
Preferred name
carbocisteine
Synonyms
CARBOCYSTEINE ()
Broncodeterge ()
Mucodyne ()
S-Carboxymethyl-L-cysteine ()
PMID28454500-Compound-50 ()
carbocisteine, Sopar ()
Rhinathiol ()
Mucodyne Fte ()
Methista ()
Dl-3-(carboxymethylthio)alanine ()
Pectox ()
Carbocisteine ()
LJ-206 ()
Carbocit ()
L-carbocysteine ()
LJ 206 ()
Mucopront ()
R05CB03 ()
Lisomucil ()
Reomucil ()
Siroxyl ()
L-carbocisteine ()
NSC-14156 ()
Transbronchin ()
Carbocisteina ()
Carbocysteine, dl- ()
Carbocistein ()
Loviscol ()
Mucocis ()
LJ206 ()
Pulmoclase ()
Mucofan ()
Muciclar ()
Mucolase ()
AHR-3053 ()
NSC-68427 ()
Carbocysteine dl-form ()
Mucolex ()
P&D ID
PD009376
CAS
29433-95-2
638-23-3
2387-59-9
Tags
available
drug
Drug Status
approved
investigational
Max Phase
3.0
Drug indication
Bronchiectasis
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Carbocisteine is a expectorant mucolytic. It significantly reduces sputum viscosity, cough, dyspnea and fatigue. Additionally, it prevents pulmonary infections by decreasing accumulated mucus in the respiratory tract. Carbocisteine is used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity. (Enamine Bioactive Compounds)
DESCRIPTION Carbocisteine (Mucodyne) is commonly used as an anti-infective nasal spray with mucolytic and expectorant effects. (TargetMol Bioactive Compound Library)
Compound Sets
12
ChEMBL Drugs
CHEMBL396416
Drug Repurposing Hub
DrugBank
DB04339
DrugBank Approved Drugs
DB04339
DrugCentral
4160
DrugCentral Approved Drugs
4160
DrugMAP
DMQPKCD
Enamine Bioactive Compounds
EBC-26139
MedChem Express Bioactive Compound Library
HY-D0205A
NPC Screening Collection
ReFrame library
TargetMol Bioactive Compound Library
T3612
External IDs
47
Properties
(calculated by RDKit )
Molecular Weight
179.03
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
5
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.78
TPSA
100.62
Fraction CSP3
0.6
Chiral centers
1.0
Largest ring
0.0
QED
0.51
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
chronic obstructive pulmonary disease (COPD)
Target
GSTP1
Apoptosis
Keap1-Nrf2
NF-κB
PERK
MOA
mucolytic agent
Pathway
Cell Cycle/DNA Damage
Source data