General
Preferred name
latamoxef
Synonyms
MOXALACTAM DISODIUM ()
Antibiotic 6059S ()
LY-127935 ()
FestamoxinLy ()
Shiomarin ()
6059 S ()
Latamoxef sodium ()
Moxalactam disodium salt ()
MOXALACTAM ()
Latamoxef Disodium ()
NSC-757107 ()
Disodium latamoxef ()
LY127935 ()
Moxam ()
Latamoxefum dinatricum ()
Latamoxef ()
P&D ID
PD009373
CAS
64953-12-4
64952-97-2
79120-38-0
Tags
natural product
drug
available
Approved by
FDA
Drug Status
investigational
approved
Drug indication
Anti-Infective
Bacterial infection
Max Phase
Phase 4
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
TOXICITY
Latamoxef produces potentially life-threatening effects which include Bleeding, Hypothrombinemia, Platelet dysfunctioning. which are responsible for the discontinuation of Latamoxef therapy.; The symptomatic adverse reactions produced by Latamoxef are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Skin rashes, Hematuria, Hyperuricemia, Pyuria, Raised serum creatinine.;
DESCRIPTION
Latamoxef is an oxacephem molecule developed by the Shionogi Research Laboratories (Osaka, Japan) . It belongs to the β-lactam class of antibacterial compounds.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
Guide to Pharmacology
NPC Screening Collection
Other bioactive compounds
ReFrame library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
49
Molecular Weight
520.1
Hydrogen Bond Acceptors
12
Hydrogen Bond Donors
4
Rotatable Bonds
9
Ring Count
4
Aromatic Ring Count
2
cLogP
-1.13
TPSA
206.3
Fraction CSP3
0.35
Chiral centers
3.0
Largest ring
6.0
QED
0.13
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Target
Antibacterial
Therapeutic Class
Antibiotics
Antiinfective Agents
Source data
