General
Preferred name
QUINESTROL
Synonyms
W-3566 ()
Ethinylestradiol 3-cyclopentyl ether ()
EE2CPE ()
Quinestrol ()
Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566 ()
NSC-759637 ()
W 3566 ()
Estrovis ()
estrogen ()
P&D ID
PD009370
CAS
152-43-2
Tags
natural product
drug
available
Approved by
FDA
Drug Status
approved
withdrawn
Drug indication
Breast cancer
Max Phase
Phase 4
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Quinestrol is a synthetic estrogen.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
16
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
364.24
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
5
Aromatic Ring Count
1
cLogP
5.23
TPSA
29.46
Fraction CSP3
0.68
Chiral centers
5.0
Largest ring
6.0
QED
0.73
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Endocrinology/Hormones
Vitamin D Related/Nuclear Receptor
Target
ER
ESR1, ESR2
Estrogen Receptor/ERR
Estrogen/progestogen Receptor
Indication
menopause
MOA
Estrogen receptor agonist
ATC
H
Therapeutic Class
Anticancer Agents
Source data
