General
Preferred name
betaine
Synonyms
BETAINE HYDROCHLORIDE ()
Chloral betaine ()
oxyneurine ()
lycine ()
Glycine betaine ()
trimethylglycine ()
Abromine ()
Cystadane ()
betaine anhydrous ()
Betaine chloride ()
Acidol Pepsin ()
Betainum muriaticum ()
Betaine HCl ()
NSC-32191 ()
NSC-3976 ()
2-(Trimethylammonio)Acetate ()
GLYCINEBETAINE ()
Cloral betaine ()
5107 ()
Cloral betaina ()
P&D ID
PD009238
CAS
590-46-5
107-43-7
2218-68-0
11042-13-0
Tags
available
drug candidate
drug
Approved by
EMA
FDA
First approval
1996
Drug indication
Inborn error of metabolism
Drug Status
investigational
approved
withdrawn
nutraceutical
illicit
Max Phase
2.0
1.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
PRICE
29
DESCRIPTION
Product in choline-betaine osmoregulatory pathway
(LOPAC library)
DESCRIPTION
Betaine chloride (Betaine hydrochloride) is an acidic form of betaine, a vitamin-like substance observed in grains and other foods; gains the amplification of DNA by decreasing the formation of secondary structure in GC-rich regions.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Betaine is found in the roots of Beta vulgaris. Betaine protects cells from environmental stress, it reduces cardiovascular disease risk and protects liver cells from alcoholic liver damage and nonalcoholic steatohepatitis. Besides, it has anti-inflammation and tumor preventing capacity. Betaine is a natural compound used in cosmetics material.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Betaine acts as a methyl group donor in the remethylation of homocysteine to methionine in patients with homocystinuria. It is indicated for the treatment of homocystinuria to decrease elevated homocysteine blood levels.
(Enamine Bioactive Compounds)
DESCRIPTION
Betaine (trimethylglycine) is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscle gain and fat loss because of its abilities to promote protein synthesis in the body.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
23
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine Bioactive Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LOPAC library
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
78
Molecular Weight
117.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.56
TPSA
40.13
Fraction CSP3
0.8
Chiral centers
0.0
Largest ring
0.0
QED
0.41
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Circadian clock protein KaiB
Endogenous Metabolite
Glycine betaine-binding periplasmic protein
MOA
Chloride channel inhibitor
ATC
N
Biosynthetic Origin
Other (Amino Acid)
Therapeutic Indication
Homocystinuria
Therapeutic Class
Metabolic Disorders
Pathway
Membrane Transporter/Ion Channel
Metabolism
Solubility
at water
Source data
