General
Preferred name
BESIFLOXACIN
Synonyms
BOL-303224-A ()
Besivance hydrochloride ()
Besifloxacin HCl ()
BESIFLOXACIN HYDROCHLORIDE ()
Besifloxacin (Hydrochloride) ()
SS-734 ()
SS734 ()
Besivance ()
Besifloxacin (as hydrochloride) ()
Besifloxacino ()
ISV-403 ()
Besifloxacine ()
P&D ID
PD009234
CAS
405165-61-9
141388-76-3
Tags
available
drug
Approved by
FDA
First approval
2009
Drug indication
Bacterial conjunctivitis
Ocular inflammation
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
46
DESCRIPTION
Besifloxacin is a fluoroquinolone compound with broad-spectrum antibacterial activity against Gram-positive and Gram-negative pathogens .
(GtoPdb)
DESCRIPTION
Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Besifloxacin is a novel 8-chloro-fluoroquinolone agent with potent, bactericidal activity against prevalent and drug-resistant pathogens. Besifloxacin has been found to inhibit production of pro-inflammatory cytokines in vitro.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
47
Molecular Weight
393.13
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
2
cLogP
3.14
TPSA
88.56
Fraction CSP3
0.47
Chiral centers
1.0
Largest ring
7.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
DNA/RNA Synthesis
Topoisomerase
Antibiotics
MOA
Antibiotic
bacterial DNA gyrase inhibitor
Indication
conjunctivitis
Pathway
Microbiology/virology
Anti-infection
Cell Cycle/DNA Damage
Source data
