General
Preferred name
HYDROXYPROGESTERONE CAPROATE
Synonyms
17¦Á-Hydroxyprogesterone hexanoate ()
17¦Á-Hydroxyprogesterone caproate ()
Primolut Depot ()
Delalutin ()
Hormofort ()
17α-Hydroxyprogesterone hexanoate ()
17α-Hydroxyprogesterone caproate ()
17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate ()
17??-Hydroxyprogesterone hexanoate ()
17??-Hydroxyprogesterone caproate ()
17¦Á-Hydroxyprogesterone hexanoate, 17¦Á-Hydroxyprogesterone caproate ()
Makena ()
Pharlon ()
Proluton Depot ()
Syngynon ()
Hydroxyprogesterone ()
Depo-proluton ()
17.alpha.-caproyloxy-p4 ()
NSC-15468 ()
Hydroxyprogesterone hexanoate ()
Caproato de hidroxiprogesterona ()
Hylutin ()
Procyte depo ()
17.alpha.-hydroxyprogesterone ()
Makena (autoinjector) ()
U-3096 ()
17-ohpc ()
17alpha-hydroxyprogesterone ()
17-Hydroxyprogesterone ()
Makena preservative free ()
Proge ()
Hidroxiprogesterona ()
17-alpha-hydroxyprogesterone ()
Caproate d'hydroxyprogesterone ()
Teralutil ()
Primolut depot ()
NSC-17592 ()
P&D ID
PD009228
CAS
630-56-8
Tags
available
drug
Approved by
FDA
First approval
1975
Drug Status
approved
withdrawn
investigational
Max Phase
4.0
Drug indication
premature birth
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Hydroxyprogesterone caproate is a synthetic progestin, a steroid.
DESCRIPTION
Hydroxyprogesterone caproate (Delalutin) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
13
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
428.29
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
0
cLogP
5.97
TPSA
60.44
Fraction CSP3
0.81
Chiral centers
6.0
Largest ring
6.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
spontaneous preterm birth
Target
AR, ESR1, ESR2, NR1H4, NR1I2, NR3C1, PGR
Progesterone Receptor
Estrogen/progestogen Receptor
ULK1
ULK2
MOA
Progesterone receptor agonist
Pathway
Autophagy
Vitamin D Related/Nuclear Receptor
Source data
