General
Preferred name
Triethylenetetramine
Synonyms
TRIENTINE HYDROCHLORIDE ()
MK-0681 ()
Trientine HCl ()
Metalite ()
Trientine Dihydrochloride ()
Syprine ()
TRIENTINE ()
TETA ()
Trien ()
Triethylene tetramine ()
Trientine (HCl) ()
Trientine-2HCl ()
TRIENTINE TETRAHYDROCHLORIDE ()
Triethylenetetramine Dihydrochloride ()
TETA 2HCl, Trientine Dihydrochloride ()
NSC-759164 ()
Trethylenetetramine ()
Triethylene tetraamine ()
NSC-443 ()
Cuvrior ()
NSC-158271 ()
TETA 4HCl ()
Trientine (hydrochloride) ()
P&D ID
PD009215
CAS
112-24-3
105093-20-7
105821-86-1
38260-01-4
181589-66-2
4961-40-4
Tags
nuisance
natural product
drug
available
Approved by
EMA
FDA
First approval
2022
1985
Drug Status
investigational
approved
Drug indication
Inborn error of metabolism
Chelating Agent
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
2
Organisms
0
Compound Sets
20
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
NCATS Inxight Approved Drugs
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Nuisance compounds in cellular assays
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
76
Properties
(calculated by RDKit )
Molecular Weight
146.15
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
7
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.92
TPSA
76.1
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.32
Structural alerts
1
Chelation
Cu
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
Chelating Agents
Telomerase Inhibitors
chelating agent
Indication
Wilson's disease
Target
CA14
Source data
