General
Preferred name
OPT-80
Synonyms
PAR-101 ()
Tiacumicin B ()
Clostomicin B1 ()
P&D ID
PD009182
Tags
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
ABSORPTION
Fidaxomicin is not systemically absorbed as shown by a plasma concentrations below the lower limit of quantification after single-dose or multiple-dose. In contrast, fecal concentrations of fidaxomicin are much higher and are concentration-dependent.; Cmax = 2 hours;; Tmax = 5.2 ng/mL; ; AUC = 14 ngâ¢hr/mL
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
1
Other bioactive compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
6
Molecular Weight
1056.43
Hydrogen Bond Acceptors
18
Hydrogen Bond Donors
7
Rotatable Bonds
13
Ring Count
4
Aromatic Ring Count
1
cLogP
6.23
TPSA
266.66
Fraction CSP3
0.63
Chiral centers
14.0
Largest ring
18.0
QED
0.07
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
RNA polymerase
MOA
DNA/RNA Synthesis inhibitor
Pathway
DNA Damage/DNA Repair
Source data
