General
Preferred name
CHLORPHENOXAMINE
Synonyms
Contristamine ()
CHLORPHENOXAMINE HYDROCHLORIDE ()
Clorfenoxamina ()
Clorevan ()
Phenoxene ()
Systral ()
Chlorphenoxamine hcl ()
P&D ID
PD009069
CAS
77-38-3
562-09-4
Tags
available
drug
drug candidate
Drug Status
approved
withdrawn
investigational
Max Phase
2.0
Drug indication
Pruritus
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. ;Target: Histamine Receptor
PRICE 52
DESCRIPTION Chlorphenoxamine is an analog of diphenhydramine. It has antimuscarinic and antihistaminic properties. It has been used as an antipruritic and antiparkinsonian agent. (BOC Sciences Bioactive Compounds)
DESCRIPTION Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic utilized as an antipruritic and antiparkinsonian agent. (TargetMol Bioactive Compound Library)
Compound Sets
10
BOC Sciences Bioactive Compounds
chlorphenoxamine-cas-77-38-3-item-268232
ChEMBL Drugs
CHEMBL2110774
CHEMBL2105980
DrugBank
DB09007
DrugCentral
617
DrugCentral Approved Drugs
617
DrugMatrix
MedChem Express Bioactive Compound Library
HY-B1607
ReFrame library
TargetMol Bioactive Compound Library
T7564
Withdrawn 2.0
DB09007
External IDs
36
Properties
(calculated by RDKit )
Molecular Weight
303.14
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
2
Aromatic Ring Count
2
cLogP
4.18
TPSA
12.47
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.79
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Immunology/Inflammation
Neuroscience
Anti-infection
Neuronal Signaling
ATC
D04AA34
R06AA06
R06AA56
Toxicity type
NULL
Target
Filovirus
Histamine Receptor
Parasite
SARS-CoV
Solubility
DMSO: ≥ 48 mg/mL
Source data