General
Preferred name
QUINAGOLIDE
Synonyms
Norprolac ()
Quinagolide hydrochloride ()
Quinagolide (hydrochloride) ()
CV205-502 hydrochloride ()
P&D ID
PD009055
CAS
87056-78-8
94424-50-7
Tags
available
drug
Drug indication
Hyperprolactinaemia
Drug Status
approved
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Quinagolide hydrochloride is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
29
Molecular Weight
395.22
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
1
cLogP
2.14
TPSA
72.88
Fraction CSP3
0.7
Chiral centers
3.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
hyperprolactinemia
Target
DRD2
Akt
Dopamine Receptor
MOA
Dopamine Receptor agonist
Biosynthetic Origin
Alkaloid
Therapeutic Indication
Antihyperprolactinemia
Therapeutic Class
CNS & PNS
Fertility Agents
Pathway
GPCR/G protein
Neuronal Signaling
PI3K/Akt/mTOR
Source data
