General
Preferred name
SODIUM CITRATE
Synonyms
Citric acid trisodium salt dihydrate ()
Trisodium citrate dihydrate ()
Citrosodine ()
Natrocitral ()
Sodium citrate (dihydrate) ()
Trisodium citrate (dihydrate) ()
Citric acid (trisodium salt dihydrate) ()
Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate ()
Sodium citrate dihydrate ()
Micralax ()
Anhydrous sodium citrate ()
E-331(III) ()
Sodium citrate, anhydrous ()
Cystoleve ()
Sodium citrate,anhydrous ()
Trisodium citrate, anhydrous ()
Cymalon ()
INS NO.331(III) ()
Isolyte E ()
Micolette ()
Sodium citrate hydrous ()
Anhydrous trisodium citrate ()
Cystemme ()
N-1560 ()
Canesten Oasis ()
INS-331(III) ()
Sodium citrate anhydrous ()
Anticoagulant Sodium Citrate ()
Urisal ()
Citric acid, trisodium salt ()
Natrii citras, dehydrate ()
Sod Cit ()
E331 ()
FEMA NO. 3026, ANHYDROUS- ()
FEMA NO. 3026 ()
Cystocalm ()
Relaxit ()
Sodium citrate hydrate ()
Natrii citras ()
P&D ID
PD009021
CAS
183748-56-3
68-04-2
6132-04-3
Tags
available
drug
Drug indication
Discovery agent
dry eye syndrome
Drug Status
approved
investigational
Max Phase
4.0
First approval
1983
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PHARMACODYNAMICS
Citrate prevents activation of the clotting cascade by chelating calcium ions. Citrate neutralizes acid in the stomach and urine, raising the pH [L790].;
TOXICITY
Overdose toxicity is mainly due to alkalosis as well as tetany or depressed heart function due to lack of free calcium [L790].;
PRICE
29
PRICE
29
DESCRIPTION
Sodium citrate (Natrocitral) is the sodium salt of citric acid.Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Sodium citrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Sodium citrate dihydrate (Trisodium citrate dihydrate) is an anticoagulant, and also used as a buffer and food preservatives.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
DrugBank
DrugBank Approved Drugs
DrugMAP
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
257.97
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
0
Aromatic Ring Count
0
cLogP
-14.24
TPSA
140.62
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
0.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
Apoptosis
Endogenous Metabolite
Pathway
Microbiology/virology
Anti-infection
Metabolic Enzyme/Protease
Source data
