General
Preferred name
Ohmefentanyl
Synonyms
P&D ID
PD008774
CAS
78995-14-9
Tags
drug candidate
Drug Status
illicit
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ohmefentanyl is a potent mu opioid receptor agonist. The structure has three chiral carbon centers with a possible eight optically active isomers. These isomers have different pharmaceutical profiles, with mu opioid receptor affinity and selectivity being highest for the (3R,4S,2'R)-(-)-cis and (3R,4S,2'S)-(+)-cis configured molecules .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
366.23
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
3.87
TPSA
43.78
Fraction CSP3
0.43
Chiral centers
3.0
Largest ring
6.0
QED
0.84
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
